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A deficiency in Stard7 in intestinal epithelial cells blocks inflammation-driven tumor development, but enhances colonic tumorigenesis in the presence of constitutive Wnt signaling

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If you're not getting enough B12, you can experience anemia, fatigue, weakness, constipation, decreased appetite, weight loss, dizziness, lightheadedness, confusion, poor memory, soreness of your tongue and mouth, and tingling and numbness in your hands and feet, according to Harvard Health Publishing

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doi: 10.1371/journal.pone.0157188 365 SeneviratneC

As protein and hydration go hand in hand, increasing protein intake must be accompanied by adequate fluid consumption